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    Are ‘Pseudodelics’ The Future For Mental Health?
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    Psychedelics, substances that produce non-ordinary states of consciousness, are currently being heralded as the therapeutic saviours for our long-standing mental health crisis, with preliminary studies showing promising results for psilocybin, MDMA and Ketamine-assisted therapy for depression, PTSD and addiction.
    However, whatever way you dress it up, the psychedelic trip and all it entails (insert here rubbing up against the darker recesses of your unconscious mind, uncontrollable vomiting and intense mystical experiences), is not for everyone. Nor is the current psychedelic-assisted therapy model, which requires weeks of therapy before and after treatment, a financially viable proposition for the biotech and pharma companies jostling for position in the psychedelic space.
    For a while now researchers have been trying to unpick what happens in our brains after ingesting psychedelics. From a biological point of view, scientists know that by activating the 5-HT2A serotonin receptor, compounds like psilocybin appear to cause the hallucinatory effects associated with psychedelics. Other changes in the brain include a shutting down of the default mode network, increased neuroplasticity, and improved connectivity between different parts of the brain.
    What is not clear is whether any one particular change or indeed all of them together are responsible for the impressive therapeutic outcomes experienced by patients receiving them in clinical trials and in other settings.
    Indeed is it even possible at all to reduce the effects of psychedelics to purely biological mechanisms of action?
    Psychedelics Without The Trip
    This is very much the hope for

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